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IVF - In Vitro Fertilization Procedures Step by Step
Advanced Fertility Center of Chicago
Gurnee & Crystal Lake, Illinois
Our IVF Success Rates
For a general description of IVF, selection of appropriate candidates, etc. - see the in vitro fertilization page
The process of in vitro fertilization - how is IVF done?
Basic screening tests are performed on both partners at all IVF clinics.
- In general, some testing of "ovarian reserve" should be done on the female prior to starting the injections. We use day 3 FSH testing as well as antral follicle counts for this purpose. The results of these tests give us some ability to predict whether her ovaries will respond well to the drugs (make sufficient follicles and eggs). The number of follicles that develop when we stimulate the woman correlates with the number of eggs that we get at the egg pickup (aspiration, retrieval) procedure. The number of eggs retrieved correlates strongly with IVF success rates.
Consents are signed by all parties.
The woman is stimulated with injected medications to develop multiple follicles in the ovaries. Each follicle contains a microscopic egg. These injections continue to stimulate follicle and egg growth and development for about 8 - 10 days.
- Details about ovarian stimulation protocols for in-vitro fertilization
- Details about the subcutaneous injectable medications
- Sample in vitro fertilization calendar of a "typical" cycle that shows the days medications are given, office visits, etc.
Blood and ultrasound testing is done every 1-3 days to monitor the development of the follicles (egg-containing structures) in the ovaries.
We need to get a minimum number of 3 follicles to develop to maturity in order to be able to proceed with the egg retrieval. About 90% of women under 40 with a normal FSH and normal antral follicle counts will develop at least this minimum number of follicles. If this many mature follicles can not be obtained from the stimulation process - we will "cancel" the cycle (not proceed to egg retrieval). Criteria for cancellation can vary between IVF centers.
Our criteria for cycle cancellation
Ultrasound picture of follicles (black circular areas) in a stimulated
ovary
Cursors outline a 15 mm follicle
When a sufficient number of the woman's follicles are mature, a transvaginal ultrasound-guided egg retrieval (egg aspiration) procedure is performed to remove the eggs from the follicles. At our IVF clinic, the average duration of the egg retrieval procedure is under 10 minutes, with a range of about 2-15 minutes. Powerful anesthesia medications are used so that the woman is "out" during this procedure and does not feel or remember anything.
Pictures of in vitro fertilization procedures
The egg aspiration procedure in progress - an egg is aspirated from a follicle
Ovary outlined in blue - area between red and blue lines is tissue at top of vagina
The needle is passed through the top of the vagina to get to the follicles and eggs.
The needle is the white line (along the white dots) on the right
The eggs are then fertilized in the laboratory with her partner's sperm. If the sperm (or the eggs) are of poor quality, the ICSI procedure might be used to aid in fertilization.
The embryos are cultured in the IVF laboratory for 2-6 days.
The embryo transfer procedure is done which places the embryos in the woman's uterus where they will hopefully implant and develop to result in a live birth. This is like a Pap smear for the woman. There should be no discomfort.
If there are leftover embryos (of sufficient quality) beyond the number that is transferred, many couples prefer to have them frozen (cryopreserved) for use in a future cycle. Embryo cryopreservation can be used for another attempt at having a baby if the "fresh" cycle fails - or as an attempt to have another child if the fresh cycle is successful.
IVF live birth success rate statistics:
Success rates for IVF procedures vary considerably by the program handling the case. This is an important factor to consider - and not well understood by many consumers of infertility and IVF services.
Make sure that you discuss pregnancy and delivery success rates in detail with your doctor before you start a cycle. You should ask about their pregnancy and delivery rates for couples similar to you (e.g. same age group and diagnosis).
Get numbers in writing from your center before getting started. Any program will be able to provide this. If they are unwilling to provide pregnancy and/or delivery rates in writing, consider going elsewhere - they probably have low pregnancy rates.
A national summary and clinic-specific IVF results for the 2007 calendar year were released in 2009 and posted on the website of The Centers for Disease Control and Prevention, CDC, a US government agency).
A national summary and clinic-specific IVF results for 2007 were also released in 2009 and posted on the website of The Society for Assisted Reproductive Technology, SART.
Our IVF live birth success rates and links to the SART and CDC websites with IVF success rates for all reputable centers are on the IVF success rates page.
Day 5 IVF embryo at the blastocyst stage
The cluster of cells on the right side are fetal cells
The other peripheral cells will become the placenta
The fluid-filled cavity of the blastocyst is on the left side
Blastocyst transfer of 2 embryos allows high pregnancy rates and almost no risk for triplets or higher
Costs of In Vitro Fertilization:
Our IVF cycle cost includes everything except medications for $9,500 (cash discounted price).
The average charge for IVF nationwide is about $12,000. Some centers charge $15,000 or more.
It is important not to equate price with quality when it comes to IVF. A program can be very expensive and have low success rates.
We also offer a 100% money-back guarantee pricing option for couples that qualify.
Related pages:
Overview of in vitro fertilization
Come here from out of Town for IVF
Previous Tubal Ligation
IVF Ovarian Stimulation
Egg Retrieval
Embryo Transfer
Embryo Freezing
Sample IVF Calendar
IVF vs Inseminations
PGD and IVF
