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Antagonist IVF Protocol Sample Calendar
In Vitro Fertilization Protocol Using Ganirelix or Cetrotide

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Ganirelix (Antagonist) IVF Protocol Calendar

USING BIRTH CONTROL PILLS

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

1

Last birth control pill (of about 17 pills)

2

Nothing

3

Nothing

4

Nothing

5

Nothing

6

Baseline blood and ultrasound

Start stimulation shots (FSH) in evening

7

Day 2 of stim

8

Day 3 of stim

9

Day 4 of stim

10

Day 5 of stim

Blood and ultrasound

11

Day 6 of stim


Start Ganirelix

12

Day 7 of stim

Blood and ultrasound

Ganirelix

13

Day 8 of stim



Ganirelix

14

Day 9 of stim

Blood and ultrasound - follicles now are ready

HCG trigger shot at night

15

16

Egg retrieval procedure

17

Fertilization check in morning

Start progesterone

18

19

Embryo transfer procedure

Day 3 transfer of cleavage stage embryos

20

21

Embryo transfer procedure

Day 5 transfer of blastocyst stage embryos

22

23

 

24

25

26

27

28

29

30
Blood pregnancy test

 

 

 

 

 

Key to antagonist IVF schedule:

Blood and ultrasound = blood test for IVF hormone values (estrogen levels in IVF stimulation are important) and transvaginal ultrasound to measure the follicle sizes in the ovaries. These visits usually take about 20-30 minutes in our offices and can be scheduled as early as 6:30AM.

Ganirelix = subcutaneous injection of a medication (GnRH antagonist). This drug is taken once daily starting on about day 6 of stimulation.

Stim = ovarian stimulation. Involves subcutaneous injection of a medication containing follicle stimulating hormone (FSH), which causes multiple follicles containing eggs to develop in the ovaries. Ovarian stimulation usually lasts about 8-11 days.

HCG injection = subcutaneous or intramuscular injection of a medication called HCG, which causes the eggs to complete the maturation process. This is taken only once in the cycle.

Progesterone = vaginal cream or suppositories or intramuscular injection of a medication (female hormone) called progesterone. This drug helps to prepare a receptive uterine lining for embryo implantation.

Egg retrieval procedure = procedure to get eggs from the ovaries

Embryo transfer procedure = procedure to put embryos in the uterus

  • The example above is a fairly typical IVF cycle.
  • Most patients will need 4 visits for monitoring the stimulation (shown as "Blood and Ultrasound" on the calendar) before the HCG trigger shot.
  • Some women will need only 3 monitoring visits and some may require 5 or even 6 visits.
  • It depends on the woman's response to the ovarian stimulating medications.
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