Advanced Fertility Center of Chicago
Advanced Ferility Center of Chicago
 

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IVF Treatment for PCOS

In Vitro Fertilization for Polycystic Ovarian Syndrome and Infertility

IVF Success Rates with PCOS

PCOS and IVF Success

The large majority of women with PCOS, polycystic ovarian syndrome, that have not gotten pregnant with other treatments will be able to get pregnant and have a baby with IVF (in vitro fertilization) if they are under 40 and do their IVF at a high quality clinic.

IVF clinics are not all the same - learn more about IVF pregnancy success rates.

Controlling Multiple Pregnancy Risks with PCOS

Our IVF PCOS Success Rates and Statistics

  • In general, IVF success rates are excellent for cases with infertility caused by PCOS
  • In our in vitro fertilization program we see PCOS pregnancy statistics of about 60% for a live birth rate per egg retrieval (woman under age 35)
  • We have had many PCOS IVF success stories...
  • See our IVF live birth success rates

IVF Protocols for PCOS

We specialize in treating women with PCOS and have 2 IVF stimulation protocols that we commonly use with PCOS:

  1. Ganirelix with Lupron trigger protocol
  2. PCOS down-regulation protocol (below)

The down-regulation PCOS IVF protocol combines:

The calendar below shows the down-regulation protocol for PCOS

  • We use metformin, usually at a dose of 500mg 3 times daily for at least a month before starting Lupron
  • Then, oral contraceptive pills for about 21 days (last 4 days of OCP shown on calendar)
  • Lupron overlaps with the last 3 birth control pills
  • Ovarian stimulation starts after 6 or 7 "pill free" days
  • Careful control of the dose of injectable FSH hormone and cautious monitoring of the ovarian response is important with polycystic ovary cases
  • We do our very best to avoid over-responding, which can result in ovarian hyperstimulation syndrome
Sunday Monday Tuesday Wednesday Thursday Friday Saturday

1

OCP

2

OCP/Lupron

3

OCP/Lupron

4

OCP/Lupron

5

Lupron

6

Lupron

7

Lupron

8

Lupron

9

Lupron

10

Lupron

11

Lupron

Start ovarian stimulation

12

Lupron

13

Lupron

14

Lupron

Day 1 of stim Day 2 of stim Day 3 of stim Day 4 of stim

15

Lupron

16

Lupron

17

Lupron

18

Lupron

19

Lupron

20

Lupron

HCG injection

21
Day 5 of stim Day 6 of stim Day 7 of stim Day 8 of stim Day 9 of stim Day 10 of stim

22

Egg retrieval

Day of fertilization

23 24

25

Day 3 transfer

26

27

Day 5 transfer

28

Key to table:

  • Lupron = subcutaneous injection of a medication called Lupron (GnRH agonist). This medication is taken once daily
  • HCG injection = injection of a medication called HCG, which causes the eggs to complete maturation. This is taken only once in the cycle.
  • Egg retrieval procedure = the procedure that gets eggs from the ovaries
  • Embryo transfer procedure = the procedure putting embryos back in the uterus
  • Most women need 4 to 6 visits for monitoring the stimulation (not shown on this calendar) before they get the HCG trigger shot
  • The duration of the ovarian stimulation process can be shorter or longer than shown. This example shows 10 days of stimulation before the HCG trigger
  • The average number of days of stimulation is 9-10, with a range of 7 to 14 days

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