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Richard Sherbahn, MD
Board Certified Reproductive Endocrinology and Infertility Specialist Doctor
Advanced
Fertility Center of Chicago
Gurnee & Crystal Lake, Illinois
Publications,
Presentations, and Research
Stained and compressed
mouse blastocyst (7 day old embryo) from endometrial coculture
Viewed with fluorescent microscopy
Red cells (trophectoderm) would become placenta
Blue cells (inner cell mass) would become fetus
Publications
Sherbahn R, Frasor J, Hibner
M, Mack S, Binor Z, Wood Molo M, Radwanska E, and Rawlins RG: Comparison of
mouse embryo development in open and microdrop coculture systems. Human
Reproduction 1996;11:2223-2229. Read the
abstract of this article
Frasor J, Sherbahn R, Binor
Z, Soltes B, Wood Molo M, Radwanska E, and Rawlins RG: Improved tubal epithelial
cell growth improves mouse embryo hatching in a coculture system. Journal of
Assisted Reproduction and Genetics 1996;13:423-430.
Sherbahn R: Spontaneous
ruptured subcapsular liver hematoma associated with pregnancy: A case report.
Journal of Reproductive Medicine 1996;41:125-128.
Presentations
"HCG levels in
heterotopic pregnancies: Can they be useful diagnostically?" Chicago
Association of Reproductive Endocrinologists, October, 1994.
"Mouse embryo
development in open and microdrop coculture systems." OB/GYN Network Day,
Rush University, April, 1995.
"Mouse embryo
development in open and microdrop coculture systems." Chicago Association
of Reproductive Endocrinologists, New Investigators Meeting , June, 1995.
"Mouse embryo
development in open and microdrop coculture systems." Surgical Sciences
Research Day, Rush University, June, 1995.
"Blastocyst transfer,
ICSI, assisted hatching and coculture." Chicago Area Resolve Annual
Meeting, May, 1999.
Abstracts
and Poster Presentations
Sherbahn R, Wood Molo M,
Binor Z, Rawlins RG, and Radwanska E. Serum HCG levels in a series of
heterotopic pregnancies. University Research Week, Rush University, Chicago,
Illinois, April, 1994.
Frasor J, Sherbahn R, Piekos
M, Hibner M, Wood Molo M, Soltes B, Binor Z, Radwanska E, and Rawlins RG:
Optimal tubal epithelium growth promotes mouse embryo hatching in co-culture.
51st Annual Meeting of the American Society for Reproductive Medicine, Seattle,
Washington, October, 1995.
Sherbahn R, Frasor J, Hibner
M, Wood Molo M, Binor Z, Radwanska E, and Rawlins RG: Coculture with human tubal
cells and endometrial cells in a microdrop under oil improves mouse embryo
development. University Research Week, Rush University, Chicago, Illinois,
April, 1996.
Borkowski A, Sherbahn R,
Radwanska E:Follicular number predicts pregnancy and multiple pregnancy rates
for human menopausal gonadotropin/intrauterine insemination cycles. University
Research Week, Rush University, Chicago, Illinois, April, 1996.
Frasor J, Sherbahn R, Sant'
Anna T, and Rawlins RG: Mouse embryo development in new media based on in vitro
human tubal epithelial cell metabolism. University Research Week, Rush
University, Chicago, Illinois, April, 1996.
Sherbahn R, Frasor J, Hibner
M, Wood Molo M, Binor Z, Radwanska E, and Rawlins RG: Coculture with human tubal
cells and endometrial cells in a microdrop under oil improves mouse embryo
development. 52nd Annual Meeting of the American Society for Reproductive
Medicine, Boston, MA, November, 1996.
Sherbahn R, Frasor J, and
Rawlins RG: Sequential coculture with human tubal and endometrial cells improves
in vitro development of mouse zygotes. 52nd Annual Meeting of the American
Society for Reproductive Medicine, Boston, MA, November, 1996.
Frasor J, Sherbahn R, Sant'
Anna T, and Rawlins RG: Mouse embryo development in new media based on in vitro
human tubal epithelial cell metabolism. 52nd Annual Meeting of the American
Society for Reproductive Medicine, Boston, MA, November, 1996.
Sherbahn, R: Optimal lead follicle size in microdose
flare IVF cycles depends on female age. 62nd
Annual Meeting of the American Society for Reproductive Medicine, New Orleans,
LA, October, 2006. Read the abstract and
details from this research study
Photographs from some of Dr. Sherbahn's Research Projects
Several mouse embryos growing in endometrial coculture system
Hatched blastocyst (7 day old embryo) at far right
Empty zona (shell that it hatched from) at top left - looks like a horseshoe
Endometrial cells in best focus at bottom right
Stained mouse
blastocyst (not compressed as in above image)
Cultured for 5 days without coculture
Stained mouse
blastocyst
Cultured for 5 days with tubal coculture
Note that more viable cells are present in this embryo
Dr. Sherbahn has been involved in research on:
Coculture -
growing the embryos in the presence of "feeder" or "helper" cells
to result in healthier embryos - with more potential for implanting and making a
baby.
Methods of improving chances for
pregnancy and delivery for "poor responder" patients.
Comparing ovarian stimulation protocols for IVF to find the best
protocol for different groups of patients.
Intrauterine insemination outcome and
the number of follicles present during ovarian stimulation.
Heterotopic (combined intrauterine and tubal) pregnancy.
Ultrasound findings during ovarian
hyperstimulation and in early pregnancy.
Evidence based medicine - outcome and
relative cost analysis for infertility therapies.
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